Complications with donating blood

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June 2, 2020 - 10:36 AM

Dear Dr. Roach: I had two blood transfusions in 2012 during an almost yearlong bout with an out of control infection that ended up in a fused knee. In a recent antibody screen, I was identified as having anti-jkb. The information on this that I was able to find on the internet was incomprehensible to me. In simple terms, what does this mean? Am I able to donate blood? Can I receive donated blood? 

— S.L.

Dr. Keith Roach

Answer: Most people know about the ABO blood types and the Rh factors that are the primary considerations that govern how we can transfuse blood, but there are many other blood antigens that can also cause transfusion reactions. “Antigen” is a general term for a substance than can provoke an immune response, usually a protein, sometimes connected with sugars. One of the families of antigens that may cause a transfusion reaction is called the Kidd blood group system. It’s named after the first patient in whom this was found. 

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